News

The MeDIAGSTOLE project aims to develop diagnostic and prognostic tools for left ventricular heart
failure with preserved ejection fraction (HF/pEF), a pathology that is difficult to diagnose and clinically
manage in the absence of targeted treatment. In this context, the University Hospital of Montpellier
and ACOBIOM decided to collaborate in order to identify biomarkers associated with this pathology,
and thus to participate in the implementation of personalized medicine for patients suffering from
this type of heart failure (HF/pEF).

Unlike DNA, which is constituted at birth and changes little over the course of Life, RNA is constantly evolving, reflecting the general state of health of the cell, organ and organism to which it belongs. RNA analysis (or gene expression analysis) is a particularly relevant approach to identify the biological markers (biomarkers) or the molecular targets associated to a biological process, a physio-pathological event, as the onset or the progression of a disease, the effects or the response to a drug or a treatment. RNA-Seq, a high throughput approach to perform RNA analysis by sequencing, become the standard technology to identify transcripts in cells and to quantify the associated expressed genes.

GEMCITEST® is a molecular diagnostic that uses blood samples to identify pancreatic cancer patients most likely to benefit from first-line gemcitabine treatment.

The abstract presented at the 2021 ASCO Annual Conference is a study synthesis of the clinical performance of the CE-IVD molecular test to assess the gemcitabine response in advanced pancreatic cancer.

Within the framework of the SME Instrument-Phase 1 call for projects, Europe provided a financial support to ACOBIOM in order to evaluate the costs of the current management of pancreatic cancer in France. This study will confirm the sale forecasts of the GemciTest in France and in Europe.

Despite a difficult context in 2020 due to the COVID pandemic, Acobiom managed to raise more than 100,000 euros on the social impact crowdfunding platform WeDoGood.

Produced by DNA, RNA is among the least known constituents of the life sciences and the least cited in publications, communications or media. RNA is delicate to use by technicians and always enigmatic for most scientists.

A scientific publication in Cancers, a peer reviewed scientific journal, presents the capabilities of Acobiom’s GemciTest® to identify the pancreatic cancer patients who are most likely to benefit from gemcitabine-based treatment as the first approach.

In a recent study, ACOBIOM, in partnering with the Jerome Lejeune Institute, characterized molecular mechanisms that could help to better understand the decreased incidence of Breast Cancer in women with Down Syndrome (Trisomy 21).

AG2R LA MONDIALE supports the improvement of medical management of pancreatic cancer with GemciTest®